Mucosal prolapse

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Introduction

Rectal prolapse refers to the abnormal protrusion of portions of the rectum through the anal canal. This protrusion may involve only the superficial mucosal layer or all layers (full-thickness). Sometimes “internal intussusception” occurs, meaning the rectum telescopes inward but has not yet protruded through the anus. Prolapse can be temporary or may progressively become permanent, affecting quality of life.

Anatomy

The rectum is the final segment of the large intestine, approximately 12-15 cm in length, and is located just before the anus. The rectum’s function is to temporarily store feces and provide conditions for controlled defecation. The rectal wall consists of multiple layers: mucosa (the surface in contact with contents), submucosa, and muscular layers (circular and longitudinal) that maintain movement and tone. Surrounding the rectum are fatty and fascial tissues that anchor it to the pelvis; this supportive structure, when weakened, leads to excessive rectal mobility and makes prolapse development easier.

Epidemiology and Risk Groups

  • Rectal prolapse is more common in women and is particularly observed in middle-aged and elderly individuals.
  • There are two specific high-risk groups: young children and adults over 50 years of age, particularly women with a history of multiple or high-risk deliveries.
  • Other associated factors that increase the likelihood of prolapse include neurological disorders that impair pelvic floor function, connective tissue diseases (such as collagen disorders), a history of pelvic or anal surgery, and a background of chronic constipation.

Important Note: Having one or more risk factors does not necessarily mean that prolapse will occur; these factors only increase the probability.

 

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Pathogenesis (Why do supportive tissues weaken?)

  1. Obstetric injury
  2. Chronic constipation and prolonged straining
  3. Neurological or muscular disorders
  4. Surgical procedures or chronic inflammation
  5. Systemic tissue weakness
  1. Obstetric Injury

  • Severe perineal tears during vaginal delivery, particularly third and fourth degree tears that involve the anal sphincter or rectal mucosa, damage the supportive structures and nerve pathways. Predisposing factors for such tears include prolonged second stage of labor, sudden fetal expulsion, use of forceps or vacuum extraction, large fetus, and multiple deliveries. If these tears are not properly treated or have inadequate repair, the long-term risk of prolapse and incontinence increases.

  1. Chronic constipation and prolonged straining

  • Repetitive intra-abdominal pressure and repeated straining cause stretching and gradual displacement of the mesorectum and supporting ligaments. Over time, these tissues become “loose” and the rectum moves forward more easily.

  1. Neurological or muscular disorders

  • Diseases that weaken the nerves controlling the pelvic floor, such as spinal cord lesions or peripheral neuropathies, compromise the supportive tissues and disrupt the rectum’s retaining function.

  1. Surgical procedures or chronic inflammation

  • Previous pelvic surgeries, adhesions, or chronic inflammation can alter the supportive architecture.

  1. Systemic tissue weakness

  • Some individuals experience reduced collagen quality and connective tissue due to connective tissue disorders or aging; this leads to decreased ligament strength and significantly increases the risk of prolapse.

Summary of mechanism: The combination of repeated increased pressure, direct injury (such as during childbirth), and changes in supportive tissue quality causes the rectum to gradually displace from its normal position and ultimately protrude.

Clinical Manifestations (Common Symptoms and Patient Complaints)

Patients typically report one or more of the following:

  • Seeing or feeling a protrusion from the anus during defecation or straining
  • A sensation of incomplete evacuation or the need to manually push the tissue back in
  • Mucous discharge, moisture, or bright blood on toilet paper
  • Gas or stool leakage due to sphincter damage or impaired control function
  • Pain or burning in the anal area—this usually occurs when the tissue becomes trapped or ulcerated
  • Sometimes symptoms coexist with other pelvic floor disorders such as bladder prolapse or a feeling of vaginal bulging

When these symptoms are recurrent or progressive and affect quality of life, it is important to be evaluated promptly.

Diagnosis of Rectal Prolapse

1. Detailed Clinical Examination

Examination is performed in both resting and straining positions to visualize the prolapse. Digital examination assesses sphincter tone and checks for any ulcers or inflammation. This examination is the first and most important step.

2. Fluoroscopic Defecography

The physician or radiologist introduces a paste with consistency similar to stool into the rectum. The patient sits on a special chair resembling a toilet, and while the fluoroscopic device records, performs several deep breaths followed by straining to document the actual process of filling and emptying. This film shows when prolapse occurs, whether internal intussusception is present, the depth of the rectocele, and how far the perineum descends. Preparation typically includes simple instructions from the radiology center or a light enema.

3. Dynamic MRI Defecography

MRI performs the same dynamic process without radiation and with greater soft tissue detail. MRI better demonstrates the mesorectum, fascia, relationship with the bladder and vagina, and internal intussusception. For patients with suspicion of multi-compartment involvement or a history of surgery or incontinence, MRI provides essential information for surgical planning.

4. Endoanal Ultrasonography and Manometry

Endoanal ultrasonography provides direct imaging of the internal and external sphincters and can show tears resulting from childbirth or scarring. Manometry measures resting and squeeze pressures of the sphincters and tells us how the muscular function is. The combination of these data determines whether the patient also needs sphincter repair.

5. Colonoscopy

Before surgery, colonoscopy is necessary to rule out concurrent polyps or tumors. If the patient has not previously had a colonoscopy, we typically schedule one.

Treatment of Rectal Prolapse

The decision-making principle is based on the severity of symptoms, the type of prolapse (mucosal or full-thickness), sphincter function, and the patient’s general condition. If the prolapse is mild and without functional impairment, we first try non-surgical treatment. If the prolapse is complete, symptomatic, or has caused ulceration/incontinence, surgery is usually the best approach.

Non-surgical treatments and home care that are low-cost and effective
  • Constipation control with diet: Daily fiber intake of at least 25-30 grams (fruits, vegetables, whole grains) and drinking 1.5-2 liters of fluids per day.
  • Stool softeners or gentle laxatives: To prevent hard stools; a common example is polyethylene glycol prescribed by a doctor.
  • Avoid prolonged straining on the toilet: Keep toilet time short.
  • Treatment and management of chronic cough: Examination to resolve lung infection or smoking cessation if smoking. Severe or prolonged daily cough increases intra-abdominal pressure and requires treatment.
  • Pelvic floor muscle exercise program: Simple Kegel exercises can be done at home — the correct way: In a comfortable position, tighten the muscles around the anal opening as if performing a “gas-holding” movement, hold for 5-10 seconds, then rest for 5-10 seconds, repeat 10 times per set and 2-3 sets per day. If you do not see results after a few weeks or are unsure about performing them, specialized pelvic floor physical therapy is beneficial.

These measures are especially effective in the early stages and for preventing progression.

A) Perineal approaches (from the front of the anus

These methods are usually chosen for elderly patients or those who cannot tolerate abdominal anesthesia. Two main methods:

  • Altemeier (Perineal rectosigmoidectomy): Removal of the rectum and a small portion of the sigmoid through a perineal incision with reconnection of the bowel ends from below. Suitable for high-risk or very elderly patients. It has faster recovery and less surgical burden but has higher recurrence rates in some reports.
  • Altemeier (Perineal rectosigmoidectomy): Removal of the rectum and a small portion of the sigmoid through a perineal incision with reconnection of the bowel ends from below. Suitable for high-risk or very elderly patients. It has faster recovery and less surgical burden but has higher recurrence rates in some reports.
B) Abdominal approaches (through the abdomen)

Abdominal methods typically provide more stable results and lower recurrence rates in younger individuals and those who are suitable for anesthesia. Two important methods:

  • Ventral Mesh Rectopexy (Anterior fixation with mesh)
  • Simple description of the method: The surgeon elevates the rectum from the front and fixes it to the anterior pelvic wall by placing a lightweight mesh or biologic tissue to maintain its normal position.
  • Why this method is popular: This method preserves the posterior nerve contact that can affect defecation function, so the likelihood of developing or worsening constipation after surgery is lower. If the prolapse is associated with rectocele or enterocele, this method can correct them simultaneously.
  • Advantages of laparoscopic/robotic approaches: When performed laparoscopically or robotically, the surgeon benefits from magnified vision and precise instruments. Greater magnification and precision allow important pelvic nerves to be better identified and preserved, reducing the risk of urinary and sexual problems. Less tissue removal, less pain, shorter hospital stay, and faster return to activity are other advantages.
  • Technical note about mesh: The type of mesh (synthetic or biologic) is selected based on the patient’s condition and the surgeon’s preference; each has advantages and risks that the surgeon should discuss with the patient.
  • Resection Rectopexy
  • This method, in addition to fixation, removes a portion of the redundant sigmoid. Suitable for patients with elongated sigmoid and resistant constipation but carries risks of anastomotic leakage (bowel connection site leakage) and depends on the surgeon’s experience.

Summary comparison: Abdominal methods provide more stable functional results, and laparoscopy/robotics can reduce complications and hospital stay duration, but the final selection should be made by a team after evaluating dynamic imaging and the patient’s general condition.

C) Transanal and stapling methods

In specific cases of mucosal prolapse or internal intussusception with evacuation disorders, methods like STARR or mucosal stapled rectopexy can be useful, but they are usually insufficient for full-thickness prolapse and patients must be selected very carefully.

When should surgery definitely be performed? (Indications)

  • Full-thickness prolapse that is significant and symptomatic.
  • Prolapse associated with mucosal ulceration, bleeding, or chronic discharge.
  • Severe functional impairment such as incontinence or inability to defecate that has not responded to conservative treatment.
  • Recurrent prolapse or tissue incarceration that threatens to become an emergency.

Choosing a Surgeon and Treatment Team: Why is Colorectal Experience Important?

  • Successful and complication-free repair of prolapse requires the surgeon’s experience in laparoscopic/robotic techniques and familiarity with pelvic nerve anatomy.

  • A good team includes a colorectal surgeon, a radiologist experienced in dynamic MRI/defecography, and a pelvic floor physical therapist. When multi-compartment prolapses exist, collaboration with a gynecologist or urologist is essential.

 Final emphasis: Sphincter repair surgeries or complex decisions should be performed by a colorectal surgeon.

Preoperative Preparation and Postoperative Care — What the Patient Should Know

  • Preoperatively, a colonoscopy is usually required to examine the entire colon.
  • Dynamic imaging (MRI or defecography) is necessary for precise surgical planning.
  • If manometry or endoanal ultrasonography indicates sphincter damage, a combined plan for sphincter repair and prolapse correction will be developed.
  • Day of surgery preparation: discontinuation or adjustment of blood thinners as directed by the surgeon, routine fasting, and following the treatment center’s instructions.
  • Hospitalization and recovery: In laparoscopic procedures, hospital stay is typically shorter (usually 1-3 days depending on condition and procedure type). Less pain, smaller incisions, and faster return to activity are advantages of the minimally invasive approach. In perineal methods, recovery time is also usually short, but bowel movements may differ.
  • Post-discharge care: Soft diet until recovery, stool softeners to prevent straining, sitz baths for local improvement, and pelvic floor physical therapy if needed. The surgeon determines the timing for return to work and strenuous activities.

Prognosis

Prognosis depends on the type of prolapse, treatment method, age, and associated diseases. Generally, surgical correction improves symptoms, and with appropriate method selection and an experienced surgeon, functional outcomes and patient satisfaction are usually good. Abdominal methods typically have lower recurrence rates, but each case must be evaluated individually.

Frequently Asked Questions about Rectal Prolapse

Does rectal prolapse always require surgery?

Not if it’s very mild and asymptomatic, but complete and symptomatic prolapse usually requires surgical treatment.

In suitable patients, yes. Laparoscopy or robotic methods provide greater visualization and magnification, along with more precise instruments, which makes protecting pelvic nerves easier, results in less postoperative pain, and allows for a quicker return to daily life. The final choice depends on the patient’s condition and the center’s experience.

If you had a third or fourth degree tear or have had symptoms of leakage or a feeling of protrusion since childbirth, you should definitely see a colorectal surgeon. Early repairs and timely follow-up significantly improve the quality of results.

A high-fiber diet and adequate fluids, stool softeners if needed, avoiding prolonged straining, and treating chronic cough; performing pelvic floor exercises at home is helpful.

Not if it’s very mild and asymptomatic, but complete and symptomatic prolapse usually requires surgical treatment.

Summary for the Patient

Rectal prolapse means the slipping or protrusion of the rectum through the anus. The causes are a combination of obstetric injury, chronic constipation, weakness of supportive tissues, and neurological or tissue factors. Diagnosis is made through examination and dynamic imaging. Simple and low-cost measures such as a high-fiber diet, stool softeners, cough treatment, and pelvic floor exercises can be helpful, but surgery is usually necessary for complete or symptomatic prolapse. If surgery is required, laparoscopic or robotic methods in experienced centers yield good results because they reduce pain, hospital stay, and the risk of nerve injury, and help with a quicker return to daily life. The final decision is made by a multidisciplinary team and a colorectal surgeon.